RAB7 Rabbit mAb,ABclonal,A12308

Reactivity

Human, Mouse, Rat

Application

WB, IP, IF/ICC, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB844396548

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameRAB7 Rabbit mAb
Cat. No.A12308
Accession NumberP51149
Gene ID (Entrez)7879
RRIDAB_2861652
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IHC-P, ELISA
Working DilutionsWB:1:55000 - 1:220000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | IF/ICC:1:1000 - 1:8000 | IHC-P:1:1000 - 1:4000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC54437
Molecular Weight23 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Synonyms

RAB7; CMT2B; PRO2706

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