RAD18 Recombinant Antibody,Bioss,bsm-61274r

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, Flow-Cyt

Conjugate

Unconjugated

Platform ID

BAB176946732

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameRAD18 Recombinant Antibody
Cat. No.bsm-61274r
Accession NumberQ9NS91
Gene ID (Entrez)56852
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, Flow-Cyt
Working DilutionsWB:1:300-5000 | Flow-Cyt:1ug/Test
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.

Synonyms

E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; RAD18; RAD18, S. cerevisiae, homolog; RING finger protein 73; RNF73.

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