RAD18 antibody [N1C1],Genetex,GTX113987

Host

Rabbit

Reactivity

Human

Application

ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB382107289

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameRAD18 antibody [N1C1]
Cat. No.GTX113987
Gene ID (Entrez)56852
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF IHC-P
ClonalityPolyclonal
Concentration0.46 mg/ml (Please refer to the vial label for the specific concentration.)
TargetRAD18
ImmunogenRecombinant protein encompassing a sequence within the center region of human RAD18. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]

Synonyms

RAD18 E3 ubiquitin protein ligase , RNF73

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.