RALBP1 antibody [11B2],Genetex,GTX83728

Host

Mouse

Reactivity

Human, Rat, Dog

Application

WB ICC/IF FCM IP

Conjugate

Unconjugated

Platform ID

BAB256611234

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameRALBP1 antibody [11B2]
Cat. No.GTX83728
Gene ID (Entrez)10928
HostMouse
IsotypeIgG1
ReactivityHuman, Rat, Dog
ConjugationUnconjugated
ApplicationWB ICC/IF FCM IP
ClonalityMonoclonal
Concentration0.84 mg/ml (Please refer to the vial label for the specific concentration.)
TargetRALBP1
ImmunogenFull length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Synonyms

ralA binding protein 1 , RIP1 , RLIP1 , RLIP76

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