RAMP2 antibody,Genetex,GTX64533
Host
Rabbit
Reactivity
Human
Application
WB
Conjugate
Unconjugated
Platform ID
BAB161245767
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq, Jul 2008]
Synonyms
receptor activity modifying protein 2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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