RANTES antibody (Biotin),Genetex,GTX12766

Host

Rabbit

Reactivity

Human

Application

WB ELISA Sandwich ELISA

Conjugate

Biotin

Platform ID

BAB713404512

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameRANTES antibody (Biotin)
Cat. No.GTX12766
Gene ID (Entrez)6352
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationBiotin
ApplicationWB ELISA Sandwich ELISA
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCCL5
ImmunogenProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hRANTES (human RANTES).
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). It is T-cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

Synonyms

C-C motif chemokine ligand 5 , D17S136E , RANTES , SCYA5 , SIS-delta , SISd , TCP228 , eoCP

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