RFX5 antibody,Genetex,GTX26557

Host

Rabbit

Reactivity

Human

Application

WB ELISA ChIP assay EMSA

Conjugate

Unconjugated

Platform ID

BAB867852870

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameRFX5 antibody
Cat. No.GTX26557
Gene ID (Entrez)5993
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ELISA ChIP assay EMSA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetRFX5
ImmunogenRFX5 (C-terminal specific) peptide corresponding to a region near the C-terminus of the human protein conjugated to KLH.
PurityIgG fractionThis product was prepared from monospecific antiserum by delipidation, salt fractionation and ion exchange chromatography.
Appearance/FormLiquid
Formulation20mM Potassium Phosphate, 150mM NaCl,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

RFX5 is the regulatory gene responsible for human MHC class II deficiency. Patients with this disease exhibit a characteristic defect in the binding of a nuclear factor, RFX, to the X box motif of MHC class II promoters. RFX5 is the 75 kDa subunit of the RFX complex, which is absolutely essential and highly specific for regulating MHC class II gene expression and control of the immune response. RFX5 is a protein consisting of 616 amino acids.

Synonyms

regulatory factor X5

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