RNA Polymerase II Subunit B1 Antibody (YA090),MedChemexpress,HY-P80883

RNA Polymerase II Subunit B1 Antibody (YA090) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RNA Polymerase II Subunit B1.

Host

Rabbit

Reactivity

Human

Application

WB,IHC-F,IHC-P,ICC/IF,IP

Conjugate

Non-conjugated

Platform ID

BAB748769139

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameRNA Polymerase II Subunit B1 Antibody (YA090)
Cat. No.HY-P80883
Accession NumberP24928
Gene ID (Entrez)5430
HostRabbit
RRIDAB_3102736
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,IHC-F,IHC-P,ICC/IF,IP
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100; IHC-F: 1:50-1:100; ICC/IF: 1:50-1:200; IP: 1:20
ClonalityRecombinant,Monoclonal
Clone NumberYA090
Molecular WeightPredicted band size: 217 kDa; Observed band size: 250 kDa
ImmunogenSynthetic peptide corresponding to Human RNA polymerase II CTD repeat YSPTSPS aa1602-1610.
Purityaffinity purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

RNA Polymerase II Subunit B1: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

Synonyms

POLR2A; POLR2; DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1

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