ROR gamma antibody,Genetex,GTX70887

Host

Rabbit

Reactivity

Human, Monkey, Bat

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB673090079

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameROR gamma antibody
Cat. No.GTX70887
Gene ID (Entrez)6097
HostRabbit
IsotypeIgG
ReactivityHuman, Monkey, Bat
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetRORC
ImmunogenSynthetic 18 amino acid peptide from ligand-binding domain of human ROR Gamma.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

RAR related orphan receptor C , IMD42 , NR1F3 , RORC , RORG , RZRG , RZRGAMMA , TOR , ROR gamma , RORγt

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