Rad18 Antibody (YA3067),MedChemexpress,HY-P83322

Rad18 Antibody (YA3067) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rad18.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,FC

Conjugate

Non-conjugated

Platform ID

BAB894221817

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

Tel: 609-228-6898
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Email:

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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameRad18 Antibody (YA3067)
Cat. No.HY-P83322
Accession NumberQ9NS91
Gene ID (Entrez)56852
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,FC
Working DilutionsWB: 1:500-1:1000; FC: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA3067
Molecular WeightPredicted band size: 56 kDa; Observed band size: 70 kDa
ImmunogenA synthesized peptide derived from human RAD18 aa50-100/495.
PurityAffinity Chromatography
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

Rad18 is an E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. It functions in gap-filling of the daughter strand during replication of damaged DNA. Rad18 associates with the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex, which mediates mono-ubiquitination of DNA-associated PCNA at 'Lys-164'. Additionally, Rad18 exhibits ssDNA binding activity.

Synonyms

E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; RAD18; RAD18; S. cerevisiae; homolog; RING finger protein 73; RNF73

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