Recombining Binding Protein Suppressor Of Hairless (RBPJ) Antibody,Abbexa,abx029503
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
Host
Rabbit
Reactivity
Human
Application
ELISA, WB, IHC, IF/ICC
Conjugate
Unconjugated
Platform ID
BAB936556429
Abbexa
Contact
Tel: +44 (0) 1223 755950
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Product Specifications
Specifications
NameRecombining Binding Protein Suppressor Of Hairless (RBPJ) Antibody
Cat. No.abx029503
Accession NumberQ06330
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsWB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 55.6 kDa
ImmunogenKLH-conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human RBPJ.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Polyclonal Antibodies
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