Retinoid X Receptor beta antibody,Genetex,GTX79265

Host

Rabbit

Reactivity

Human, Mouse, Bovine

Application

WB IP ChIP assay Gel supershift assays IHC

Conjugate

Unconjugated

Platform ID

BAB432160723

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameRetinoid X Receptor beta antibody
Cat. No.GTX79265
Gene ID (Entrez)20182
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Bovine
ConjugationUnconjugated
ApplicationWB IP ChIP assay Gel supershift assays IHC
ClonalityPolyclonal
TargetRxrb
ImmunogenSynthetic peptide corresponding to residues Q(190) K S D Q G V E G P G A T(202) of mouse RXR beta.
PurityUnpurified
Appearance/FormLiquid
FormulationSerum,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta, also known as RCoR-1, controls such a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR). The corresponding gene for the retinoid X receptor beta is NR2B2.

Synonyms

retinoid X receptor beta , AL023085 , H-2RIIBP , Nr2b2 , RCoR-1 , Rub

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