Rev-Erbα/NR1D1 Rabbit mAb,ABclonal,A20452

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB471907842

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameRev-Erbα/NR1D1 Rabbit mAb
Cat. No.A20452
Accession NumberP20393
Gene ID (Entrez)9572
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IF-P, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IF/ICC:1:100 - 1:400 | IF-P:1:100 - 1:400 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC50483
Molecular Weight75kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.

Synonyms

EAR1; hRev; THRA1; THRAL; ear-1; REVERBA; REVERBalpha; Rev-Erbα/NR1D1

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