Rpb1 CTD Rabbit mAb,ABclonal,A28326

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IHC-P, ChIP, ELISA

Conjugate

Unconjugated

Platform ID

BAB345745900

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameRpb1 CTD Rabbit mAb
Cat. No.A28326
Accession NumberP24928
Gene ID (Entrez)5430
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IHC-P, ChIP, ELISA
Working DilutionsWB:1:8000 - 1:40000 | IF/ICC:1:100 - 1:500 | IHC-P:1:2500 - 1:10000 | ChIP:3μg antibody for 10μg-15μg of Chromatin | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000)，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC70612
Molecular Weight250 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Synonyms

RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; NEDHIB; RpIILS; hsRPB1; hRPB220

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