S100B Monoclonal Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-10832m-bf680-100ul

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB, FCM, IF(IHC-P)

Conjugate

AbBy Fluor-680

Platform ID

BAB567338105

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameS100B Monoclonal Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-10832m-bf680-100ul
Accession NumberP04271
Gene ID (Entrez)6285
HostMouse
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationAbBy Fluor-680
ApplicationWB, FCM, IF(IHC-P)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IF(IHC-P):IFIHC-P1:100-500
ClonalityMonoclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Synonyms

NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium binding protein beta chain; S100 calcium-binding protein B; S100 protein beta chain; S100B_HUMAN; S100beta; S100 β; S100-β; S100β.

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