S1PR5 / EDG8 antibody,Genetex,GTX71425

Host

Rabbit

Reactivity

Human, Rat, Pig, Monkey, Bat

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB423364947

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameS1PR5 / EDG8 antibody
Cat. No.GTX71425
Gene ID (Entrez)53637
HostRabbit
IsotypeIgG
ReactivityHuman, Rat, Pig, Monkey, Bat
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetS1PR5
ImmunogenSynthetic 17 amino acid peptide from N-terminal extracellular domain of human S1PR5 / EDG8.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]

Synonyms

sphingosine-1-phosphate receptor 5 , EDG8 , Edg8 , S1P5 , S1PR5 , SPPR1 , SPPR2 , sphingosine1phosphate receptor 5

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