SARM1 antibody,Genetex,GTX131411
Host
Rabbit
Reactivity
Human, Mouse, Drosophila
Application
WB ICC/IF
Conjugate
Unconjugated
Platform ID
BAB780883371
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameSARM1 antibody
Cat. No.GTX131411
Gene ID (Entrez)23098
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Drosophila
ConjugationUnconjugated
ApplicationWB ICC/IF
ClonalityPolyclonal
Concentration0.64 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSARM1
ImmunogenRecombinant protein encompassing a sequence within the C-terminus region of human SARM1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
Synonyms
sterile alpha and TIR motif containing 1 , MyD88-5 , SAMD2 , SARM
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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