SARS-CoV-2 Spike Glycoprotein Antibody,Abbexa,abx376478

SARS-CoV-2/COVID-19 Spike Glycoprotein Antibody is a chimaeric recombinant Monoclonal antibody expressed in CHO cells against SARS-CoV-2 Spike Glycoprotein, containing Mouse variable region and Human IgG1 Kappa constant region. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Host

Human, Mouse

Reactivity

Virus

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB989619682

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameSARS-CoV-2 Spike Glycoprotein Antibody
Cat. No.abx376478
HostHuman, Mouse
IsotypeIgG1 Kappa
ReactivityVirus
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsELISA: 1/5000 - 1/10000, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
Concentration2 mg/ml
ImmunogenRecombinant SARS-CoV-2 S1 protein.
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.5.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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