SCYL2 antibody,Genetex,GTX00732

Host

Rabbit

Reactivity

Human, Mouse, Rat, Hamster

Application

WB ICC/IF IP

Conjugate

Unconjugated

Platform ID

BAB839177905

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSCYL2 antibody
Cat. No.GTX00732
Gene ID (Entrez)55681
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Hamster
ConjugationUnconjugated
ApplicationWB ICC/IF IP
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSCYL2
ImmunogenHuman SCYL2 protein (amino acids 528-929) fused with a 6 * His tag
PurityPurified IgG by Salting-out and ion-exchange chromatography
Appearance/FormLiquid
FormulationPBS, 50% Glycerol,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]

Synonyms

SCY1 like pseudokinase 2 , CVAK104

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