SDHA Antibody (YA083),MedChemexpress,HY-P80318

SDHA Antibody (YA083) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SDHA.

Host

Rabbit

Reactivity

Human,Mouse,Rat,Zebrafish

Application

WB,ICC/IF,IHC-P,FC

Conjugate

Non-conjugated

Platform ID

BAB814548814

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Verification Image
Scientific Background

Specifications

NameSDHA Antibody (YA083)
Cat. No.HY-P80318
Accession NumberP31040
Gene ID (Entrez)6389
HostRabbit
RRIDAB_3102886
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat,Zebrafish
ConjugationNon-conjugated
ApplicationWB,ICC/IF,IHC-P,FC
Working DilutionsWB: 1:500-1:1000; ICC/IF: 1:50-1:200; IHC-P: 1:50-1:5000; FC: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA083
Molecular WeightPredicted band size: 73 kDa; Observed band size: 70 kDa
ImmunogenSynthetic peptide corresponding to Human SDHA.AA range:581-624.
PurityProtein A affinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

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Scientific Background

SDHA is the flavoprotein (FP) subunit of succinate dehydrogenase (SDH), which participates in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (by similar). Enol-oxaloacetate, a potent inhibitor of succinate dehydrogenase activity, can be further isomerized into keto-oxaloacetate (by similar). Additionally, SDHA can function as a tumor suppressor.

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