SDHD antibody,Genetex,GTX60136

Host

Rabbit

Reactivity

Human, Rat

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB264718605

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSDHD antibody
Cat. No.GTX60136
Gene ID (Entrez)6392
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSDHD
ImmunogenKLH conjugated synthetic peptide derived from human SDHD(120-159).
PurityProtein A purified
Appearance/FormLiquid
Formulation1% BSA, 50% Glycerol,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Synonyms

succinate dehydrogenase complex subunit D , CBT1 , CII-4 , CWS3 , PGL , PGL1 , QPs3 , SDH4 , cybS

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