SET/TAF1 Rabbit mAb,ABclonal,A9173

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IF/ICC, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB844496500

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSET/TAF1 Rabbit mAb
Cat. No.A9173
Accession NumberQ01105
Gene ID (Entrez)6418
RRIDAB_2863678
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, IP, ELISA
Working DilutionsWB:1:500 - 1:2000 | IHC-P:1:50 - 1:200 | IF/ICC:1:50 - 1:200 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC1462
Molecular Weight37kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

2PP2A; IGAAD; MRD58; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA; SET/TAF1

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