SFRP4 Antibody (YA1943),MedChemexpress,HY-P82198

SFRP4 Antibody (YA1943) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SFRP4.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB887225177

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameSFRP4 Antibody (YA1943)
Cat. No.HY-P82198
Accession NumberQ6FHJ7
Gene ID (Entrez)6424
HostRabbit
RRIDAB_3104311
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityRecombinant,Monoclonal
Clone NumberYA1943
Molecular WeightPredicted band size: 40 kDa; Observed band size: 53-55 kDa
ImmunogenA synthetic peptide of human SFRP4
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

SFRP4, a member of the soluble frizzled-related proteins (sFRPs), serves as a modulator of Wnt signaling through its direct interaction with Wnts. Demonstrating functional similarities to other sFRPs, SFRP4 contributes to the regulation of cell growth and differentiation in specific cell types. Notably, it plays a crucial role in bone morphogenesis and may act as a regulator of adult uterine morphology and function. Additionally, SFRP4 is implicated in increasing apoptosis during ovulation, potentially through the modulation of FZ1/FZ4/WNT4 signaling. Furthermore, it exhibits phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. These diverse functions underscore the versatile regulatory role of SFRP4 in various cellular processes and physiological contexts.

Synonyms

FRP4; FrpHE; PYL; Sfrp4

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