SH3 Domain Binding Protein 1 (SH3BP1) Antibody,Abbexa,abx029169

SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).

Host

Rabbit

Reactivity

Human

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB554872139

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameSH3 Domain Binding Protein 1 (SH3BP1) Antibody
Cat. No.abx029169
Accession NumberQ9Y3L3
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 75.7 kDa
TargetSH3BP1
ImmunogenKLH-conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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