SHANK1 antibody [C3], C-term,Genetex,GTX107701

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB495575327

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameSHANK1 antibody [C3], C-term
Cat. No.GTX107701
Gene ID (Entrez)50944
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr
ClonalityPolyclonal
Concentration0.53 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSHANK1
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SHANK1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 10% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Synonyms

SH3 and multiple ankyrin repeat domains 1 , SPANK-1 , SSTRIP , synamon

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