SHANK3 antibody,Genetex,GTX133133

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB ICC/IF IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB470676020

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSHANK3 antibody
Cat. No.GTX133133
Gene ID (Entrez)58234
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-Fr
ClonalityPolyclonal
Concentration0.39 mg/ml (Please refer to the vial label for the specific concentration.)
TargetShank3
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse SHANK3. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Synonyms

SH3 and multiple ankyrin repeat domains 3 , AI841104 , SHANK3c-3 , SHANK3c-4 , Shank3b

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