SHMT1 antibody [AT26E5],Genetex,GTX57666

Host

Mouse

Reactivity

Human, Mouse

Application

WB ICC/IF

Conjugate

Unconjugated

Platform ID

BAB264018941

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSHMT1 antibody [AT26E5]
Cat. No.GTX57666
Gene ID (Entrez)6470
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSHMT1
ImmunogenThe clone AT26E5 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SHMT3 protein.
PurityProtein A Purified
Appearance/FormLiquid
FormulationPBS, 10% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Synonyms

serine hydroxymethyltransferase 1 , CSHMT , SHMT , SHMT1

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