SIN3B antibody [N1N2-2], N-term,Genetex,GTX116417

Host

Rabbit

Reactivity

Human, Mouse

Application

WB ICC/IF IP

Conjugate

Unconjugated

Platform ID

BAB450685620

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameSIN3B antibody [N1N2-2], N-term
Cat. No.GTX116417
Gene ID (Entrez)23309
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF IP
ClonalityPolyclonal
Concentration0.57 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSIN3B
ImmunogenRecombinant protein encompassing a sequence within the center region of human SIN3B. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

Synonyms

SIN3 transcription regulator family member B

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