SIRT1 antibody [1F3],Genetex,GTX82793

Host

Mouse

Reactivity

Human, Rat

Application

WB ICC/IF IHC-P FCM ELISA

Conjugate

Unconjugated

Platform ID

BAB878125408

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSIRT1 antibody [1F3]
Cat. No.GTX82793
Gene ID (Entrez)23411
HostMouse
IsotypeIgG1
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM ELISA
ClonalityMonoclonal
TargetSIRT1
ImmunogenPurified recombinant fragment of human SIRT1 expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Synonyms

sirtuin 1 , SIR2 , SIR2L1 , SIR2alpha

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