SIRT6 Rabbit mAb,ABclonal,A28245
Reactivity
Human, Mouse, Rat
Application
WB, IP, IF/ICC, IHC-P, ELISA
Conjugate
Unconjugated
Platform ID
BAB033239653
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
NameSIRT6 Rabbit mAb
Cat. No.A28245
Accession NumberQ8N6T7
Gene ID (Entrez)51548
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IHC-P, ELISA
Working DilutionsWB:1:3000 - 1:6000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | IF/ICC:1:100 - 1:200 | IHC-P:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000)，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC76352
Molecular Weight36-42 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
SIR2L6; hSIRT6
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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