SLC16A3/MCT4 Rabbit mAb,ABclonal,A27772

Reactivity

Human

Application

WB, IF/ICC, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB412625047

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameSLC16A3/MCT4 Rabbit mAb
Cat. No.A27772
Accession NumberO15427
Gene ID (Entrez)9123
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF/ICC, IHC-P, ELISA
Working DilutionsWB:1:5000 - 1:10000 | IF/ICC:1:100 - 1:200 | IHC-P:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC74252
Molecular Weight40kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).

Synonyms

MCT3; MCT4; MCT 3; MCT 4; MCT-3; MCT-4

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