SMRT antibody [1542],Genetex,GTX70248

Host

Mouse

Reactivity

Human

Application

WB IP

Conjugate

Unconjugated

Platform ID

BAB672190511

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSMRT antibody [1542]
Cat. No.GTX70248
Gene ID (Entrez)9612
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IP
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNCOR2
ImmunogenA synthetic peptide from the human SMRT protein corresponding to amino acids 994-1005 (ASASDPHREKTQ) coupled to KLH.
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]

Synonyms

nuclear receptor corepressor 2 , CTG26 , N-CoR2 , SMAP270 , SMRT , SMRTE , SMRTE-tau , TNRC14 , TRAC , TRAC-1 , TRAC1

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