SOX2 Rabbit PolymAb®,ABclonal,A19118PM

Reactivity

Human, Mouse, Rat

Application

WB, IP, IF/ICC, IF-P, IHC-P, ChIP, ELISA

Conjugate

Unconjugated

Platform ID

BAB867085652

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSOX2 Rabbit PolymAb®
Cat. No.A19118PM
Accession NumberP48431
Gene ID (Entrez)6657
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IF-P, IHC-P, ChIP, ELISA
Working DilutionsWB:1:3000 - 1:15000 | IP:0.5μg-4μg antibody for 500μg-700μg extracts of whole cells | IF/ICC:1:50 - 1:200 | IF-P:1:50 - 1:200 | IHC-P:1:200 - 1:800 | ChIP:3μg antibody for 10μg-15μg of Chromatin | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight35 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Synonyms

ANOP3; MCOPS3

Category Paths

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