SP1 Rabbit mAb,ABclonal,A19649

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IF/ICC, ELISA, ChIP, ChIP-seq, CUT&Tag

Conjugate

Unconjugated

Platform ID

BAB094221632

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSP1 Rabbit mAb
Cat. No.A19649
Accession NumberP08047
Gene ID (Entrez)6667
RRIDAB_2862714
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, ELISA, ChIP, ChIP-seq, CUT&Tag
Working DilutionsWB:1:1000 - 1:2000 | IHC-P:1:200 - 1:2000 | IF/ICC:1:100 - 1:400 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP:5μg antibody for 10μg-15μg of Chromatin | ChIP-seq:1:50 - 1:100 | CUT&Tag:10⁵ cells /1 μg
Clone NumberARC0128
Molecular Weight90kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms

SP1

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