SPHK2 Rabbit pAb- ABclonal,ABclonal,A25760

Reactivity

Human

Application

IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB602856221

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameSPHK2 Rabbit pAb- ABclonal
Cat. No.A25760
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIF/ICC, ELISA
Working DilutionsIF/ICC:1:100 - 1:500 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular WeightRefer to figures
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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