SRP72 Antibody (YA5988),MedChemexpress,HY-P86296

SRP72 is a component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the ER membrane. It targets the ribosome-nascent chain complex to the SRP receptor (SR), anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER. SRP72 binds the signal recognition particle RNA (7SL RNA) in the presence of SRP68 and can bind 7SL RNA with low affinity independently. by similar: The SRP complex may participate in the elongation arrest function.

SRP72; Signal recognition particle subunit SRP72 ; SRP72; Signal recognition particle 72 kDa protein;