STING/TMEM173 Rabbit mAb,ABclonal,A21051

Reactivity

Human, Mouse, Rat

Application

WB, IP, IF/ICC, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB907477519

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSTING/TMEM173 Rabbit mAb
Cat. No.A21051
Accession NumberQ86WV6
Gene ID (Entrez)340061
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IF-P, IHC-P, ELISA
Working DilutionsWB:1:2000 - 1:20000 | IP:0.5μg-4μg antibody for 600μg-1000μg extracts of whole cells | IF/ICC:1:200-1:800 | IF-P:1:200-1:800 | IHC-P:1:1000 - 1:5000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC57967
Molecular Weight37kDa/40kDa/
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Synonyms

ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; STING/TMEM173

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