STK33 Rabbit mAb,ABclonal,A19803

Reactivity

Human, Mouse

Application

WB, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB480103906

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSTK33 Rabbit mAb
Cat. No.A19803
Accession NumberQ9BYT3
Gene ID (Entrez)65975
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:500 - 1:2000 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC2330
Molecular Weight58kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Serine/threonine protein kinase (STK33) is a 524-residue kinase that belongs to the calcium/calmodulin-dependent family of kinases. STK33 exhibits differential expression in normal and malignant cancer tissue, including hepatocellular carcinoma. STK33 expression is required in the context of mutant KRAS, the most commonly mutated human oncogene, to maintain for cellular viability and proliferation. STK33 depletion via modulation of interacting proteins results in proteasome-mediated degradation of STK33 in human cancer cells, triggering apoptosis.

Synonyms

STK33

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