STXBP2 Rabbit pAb- ABclonal,ABclonal,A12511

Reactivity

Human, Mouse

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB606754349

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameSTXBP2 Rabbit pAb- ABclonal
Cat. No.A12511
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight66kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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