SV40 T-antigen antibody [PAb419],Genetex,GTX16848

Host

Mouse

Reactivity

Simian virus 40

Application

WB ICC/IF IHC-P IP

Conjugate

Unconjugated

Platform ID

BAB230646232

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameSV40 T-antigen antibody [PAb419]
Cat. No.GTX16848
HostMouse
IsotypeIgG2a
ReactivitySimian virus 40
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IP
ClonalityMonoclonal
Concentration0.1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenFull length protein (SV40).
PurityAffinity purified with antigen
Appearance/FormLiquid
Formulation50mM Sodium Phosphate, 0.2% Gelatin,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

Synonyms

Simian virus 40 T antigen ( Large T) , SV40 virus T antigen ( Large T)

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