Serotonin transporter Rabbit pAb- ABclonal,ABclonal,A28369

Reactivity

Mouse, Rat

Application

WB, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB519884802

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameSerotonin transporter Rabbit pAb- ABclonal
Cat. No.A28369
RRID#N/A
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IHC-P:1:100 - 1:400 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000),a sequential dilution method is strongly recommended to ensure measurement accuracy.
Molecular Weight83 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Enables neurotransmitter transmembrane transporter activity; nitric-oxide synthase binding activity; and serotonin:sodium:chloride symporter activity. Involved in several processes, including nervous system development; platelet aggregation; and serotonin uptake. Located in focal adhesion and synapse. Is expressed in several structures, including early conceptus; heart; liver; nervous system; and ovary. Used to study autism spectrum disorder and sudden infant death syndrome. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anxiety disorder (multiple); depressive disorder (multiple); heart disease (multiple); and substance abuse (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4).

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