Sialosyl-Tn antigen antibody [STn 219],Genetex,GTX82967

Host

Mouse

Reactivity

Human

Application

ICC/IF IHC-P IHC

Conjugate

Unconjugated

Platform ID

BAB691081439

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSialosyl-Tn antigen antibody [STn 219]
Cat. No.GTX82967
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF IHC-P IHC
ClonalityMonoclonal
Concentration0.20 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenOvine submaxillary mucin (OSM)
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers including breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase: ST6GalNAc I, which catalyzes the transfer of a sialic acid residue in alpha2,6-linkage to the GalNAcalpha1-O-Ser/Thr structure. The resulting disaccharide (Neu5Acalpha2-6GalNAcalpha1-O-Ser/Thr) cannot be further elongated and sialyl-Tn expression results therefore in a shortening of the O-glycan chains

Synonyms

CD175s antibody , Sialosyl Tn antibodys , Tn antibody

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