Siglec-5 antibody [6D33],Genetex,GTX53003

Host

Mouse

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB561532388

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSiglec-5 antibody [6D33]
Cat. No.GTX53003
Gene ID (Entrez)8778
HostMouse
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetSIGLEC5
ImmunogenHuman recombinant Siglec-5 EC domain
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]

Synonyms

CD170 , CD33L2 , OBBP2 , SIGLEC5 , sialic acid binding Ig like lectin 5

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