Sodium Potassium ATPase alpha 2 antibody,Genetex,GTX87004

Host

Rabbit

Reactivity

Human, Monkey

Application

WB

Conjugate

Unconjugated

Platform ID

BAB639195092

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameSodium Potassium ATPase alpha 2 antibody
Cat. No.GTX87004
Gene ID (Entrez)477
HostRabbit
IsotypeIgG
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetATP1A2
ImmunogenThe antiserum was produced against synthesized peptide derived from human Sodium Potassium ATPase alpha 2 (971-1020).
PurityPurified by antigen-affinity chromatographyFrom serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]

Synonyms

ATP1A2 , ATPase Na+/K+ transporting subunit alpha 2 , FHM2 , MHP2 , alpha 2 Sodium Potassium ATPase , NaK ATPase alpha 2

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