Sorbitol Dehydrogenase (SORD) Antibody,Abbexa,abx028557

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB614332320

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Abbexa

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Email:

[email protected]

Product Specifications

Specifications

NameSorbitol Dehydrogenase (SORD) Antibody
Cat. No.abx028557
Accession NumberQ00796
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 38.3 kDa
ImmunogenKLH-conjugated synthetic peptide between 211-239 amino acids from the Central region of human SORD.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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