Spark Blue™ 515 anti-human CD27 Antibody , CD27, O323,BioLegend,302868
Host
Mouse
Reactivity
Human, Cynomolgus, Rhesus
Application
FC - Quality tested
Platform ID
BAB886298954
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameSpark Blue™ 515 anti-human CD27 Antibody , CD27, O323
Cat. No.302868
HostMouse
RRIDAB_2941466 (BioLegend Cat. No. 302867)AB_2941466 (BioLegend Cat. No. 302868)
IsotypeMouse IgG1, κ
ReactivityHuman, Cynomolgus, Rhesus
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberO323
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD27
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Blue™ 515 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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