Spark Blue™ 550 anti-human TCR Cβ1 (Flexi-Fluor™) Antibody, TCR Cβ1, JOVI.1,BioLegend,285275

Clone JOVI.1 can interfere with the binding of clone IP26 on target cells.

Host

Mouse

Reactivity

Human

Application

FC

Platform ID

BAB553602403

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameSpark Blue™ 550 anti-human TCR Cβ1 (Flexi-Fluor™) Antibody, TCR Cβ1, JOVI.1
Cat. No.285275
HostMouse
RRIDAB_3683205 (BioLegend Cat. No. 285275)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC
ClonalityMonoclonal
Clone NumberJOVI.1
Concentration0.2 mg/mL
TargetTCR Cbeta1
ImmunogenTransgenic mouse lymphocytes expressing human Vβ3-Cβ1 TCR
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Blue™ 550 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The T cell receptor beta chain constant region-1 (TCR Cβ1), also known as TRBC1, is a segment of the TCR beta chain that forms the constant region of the T cell receptor. The rearrangement of TCR genes during T cell development leads to the selection of one of two TCR beta constant regions – C1 or C2.  Detection of TRBC1 within a comprehensive T cell panel can be used as evidence of clonality akin to the use of kappa/lambda light chain detection in the diagnosis of plasma cell malignancies.

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