Spark Blue™ 574 anti-human TCR Vδ2 (Flexi-Fluor™) Antibody, TCR Vδ2, B6,BioLegend,285163

Host

Mouse

Reactivity

Human

Application

FC

Platform ID

BAB832824634

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameSpark Blue™ 574 anti-human TCR Vδ2 (Flexi-Fluor™) Antibody, TCR Vδ2, B6
Cat. No.285163
HostMouse
RRIDAB_3662503 (BioLegend Cat. No. 285163)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC
ClonalityMonoclonal
Clone NumberB6
Concentration0.2 mg/mL
TargetTCR Vdelta2
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Blue™ 574 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.

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