Spark Blue™ 574 anti-mouse CD3 Antibody, CD3, 17A2,BioLegend,100275

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB730362575

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameSpark Blue™ 574 anti-mouse CD3 Antibody, CD3, 17A2
Cat. No.100275
HostRat
RRIDAB_2904266 (BioLegend Cat. No. 100275)AB_2904266 (BioLegend Cat. No. 100276)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number17A2
Concentration0.5 mg/mL
TargetCD3
ImmunogenγδTCR-positive T-T hybridoma D1
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Blue™ 574 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

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