Spark PLUS B574™ anti-mouse CD20 Antibody, CD20, SA275A11,BioLegend,150444
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB639261267
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameSpark PLUS B574™ anti-mouse CD20 Antibody, CD20, SA275A11
Cat. No.150444
HostRat
RRIDAB_3717243 (BioLegend Cat. No. 150443)AB_3717243 (BioLegend Cat. No. 150444)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberSA275A11
Concentration0.2 mg/mL
TargetCD20
ImmunogenMouse CD20 - transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with Spark PLUS B574™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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